The IMMUNOBIOGRAM® report and how to interpret it?

Published On: October 15th, 2021

The IMMUNOBIOGRAM® is a blood-based in vitro diagnostic (IVD) bioassay that measures the pharmacodynamic response to individual immunosuppressive drugs.

The IMMUNOBIOGRAM® -RENAL TRANSPLANT report provides individualized information on the patient response and evolution to the current therapy and to the mostly-used immunosuppressants.

There are two key concepts to keep in mind when analyzing the response to immunosuppressants:

  • Sensitivity to the drugs: The higher the sensitivity, the better response to the drug.
  • Probability of rejection multiplier: There is an increase in the probability of rejection as the patient has less sensitivity to the drugs.

The report contains the following information: 

  1. Patient’s data
  2. Current Treatment results: The evolution of the patient with the scheduled treatment is shown for the dates the Immunobiograms have been performed.
  3. Results by immunosuppressant: It shows the evolution for each of the most commonly-used scheduled and non-scheduled immunosuppressants for the dates the Immunobiograms have been performed.
  4. Interpretation guide: The report is accompanied by a help guide, which together with other clinical variables, seeks to facilitate the doctor’s decision-making.

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